右美托咪定对室上性心律失常的电生理研究

　　TirottaCF,NguyenT,FishbergerS，Dexmedetomidineuseinpatientsundergoingelectrophysiologicalstudyforsupraventriculartachyarrhythmias.PaediatrAnaesth，

Abstract:

BACKGROUND：Dexmedetomidineisaselectivealpha-2adrenergicagonistwithsedative,analgesic,andanxiolyticproperties.Dexmedetomidinehasnotbeenapprovedforuseinpediatrics.Dexmedetomidinehasbeenreportedtodepresssinusnodeandatrioventricularnodalfunctioninpediatricpatients;ithasbeensuggestedthattheuseofdexmedetomidinemaynotbedesirableduringelectrophysiologicalstudiesAIM:Wehypothesizethattheuseofdexmedetomidinedoesnotinhibittheinductionofsupraventriculartachyarrhythmias(SVT)duringelectrophysiologicalstudiesanddoesnotinhibittheablationofsucharrhythmias.METHODS:Inthisretrospective,observationalcohortstudy,wereviewedallcasespresentingtothecardiaccatheterizationlaboratoryfordiagnosisortreatmentofSVTsince.Allcaseswereperformedbythesameelectrophysiologist.Theanesthesiawasprovidedbyoneofthethreecardiacanesthesiologists.Onecardiacanesthesiologistdidnotusedexmedetomidineduringelectrophysiologicalstudies.Aseconduseddexmedetomidine,butonlywithaninfusion.Thethirduseddexmedetomidinewithaprimarybolusandaninfusion.Thus,thepatientswerestratifiedintothreedifferentgroups:Group1patientsdidnotreceiveanydexmedetomidine.Group2patientsreceivedadexmedetomidineinfusionof0.5-1μg·kg-1·h-1.Group3patientsreceivedadexmedetomidineinfusionof0.5-1μg·kg-1·h-1andadexmedetomidineboluspriortotheinfusionof0.5-1μg·kg-1.Wethen







































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